DNAzyme
case study
UV protection enzymes from Antarctic microorganisms
Pre-Seed
Uruguay

What's the Problem?

Skin cancer statistics currently underestimate its true prevalence, with up to 3 million cases officially reported each year. This underestimation occurs due to the complexity of the diagnosis. In addition, the problem extends beyond skin cancer, as daily exposure to UV radiation leads to photoaging and other skin diseases. Current methods of UV protection lack efficient DNA repair, leading to the appearance of mutations that cause skin diseases. Current solutions include topical products with plankton extracts that claim to contain repairing photolyases. However, their efficacy, purity, and non-allergenicity are not empirically proven. These limitations demand a reliable solution that ensures mutation-free DNA repair and addresses the shortcomings of current offerings.

DNAzyme
DNAzyme
DNAzyme
DNAzyme

How are they Solving it?

We offer a solution derived from Antarctic extremophiles and their next-generation photolyases. After 10 years of research, we have selected new photolyases, with improved DNA repair activity and compatibility for recombinant expression in E. coli. This compatibility was not possible with plankton-derived photolyases. Our next-generation photolyases provide superior repair activity, exceeding the current industry standard and overcoming the limitations of existing plankton-derived alternatives. Through our innovative approach, we achieve more than 60% DNA repair efficiency in in vivo models while maintaining a high level of purity of 90%.

Alytix

Next Startup

Alytix