What's the Problem?
We all know someone who, had they received an early diagnosis, would still be with us, someone whose quality of life would be much better if they had had a portable monitoring tool for their health. Someday we may even be the ones who depend on these tools. We don't have to look far to know that we need ultra-fast and portable diagnostic devices. The pandemic has shown us that the problems of speed, accessibility, and simplicity are far from being solved. Even with all the existing technological advances, laboratory equipment still requires the processing and purification of samples, as well as expensive and complex laboratory equipment for their reading. It is impossible to miniaturize existing diagnostic tools without losing their sensitivity. If we really want to solve all these problems, we must think of new solutions, which involve the use of new technologies. Portable, ultrasensitive diagnostic tools are going to power the revolution of real-time health monitoring by empowering patients, and democratizing access to quality testing and monitoring for everyone, regardless of where they live.
How are they Solving it?
The future of biosensor-powered diagnostics relies on how well, and accurately we can transform biological signals into digital results. Doing this requires a bio-electronic interphase that can detect biological interactions, and biochemical reactions, and convert them to machine language, ones and zeroes. We have developed a graphene based chipset that can do exactly that. By integrating modern electronic chipsets with biorecognition elements we can detect biologic signals in real time. Our nanochip, a graphene based transistor the size of a quarter, can detect target analytes in serum, saliva or urine from a patient, and provide results within 5 minutes. We have developed so far an ultra-rapid antigen detection kit based on these graphene sensors, that has a sensitivity on-par with PCR assays, but provides results within minutes with 1-2 drops of sample. We have also designed and tested a biosensor that can analyze and detect the presence of IL-6, on par with the newest ELISA methods, for a fraction of it’s cost, and within minutes.